Gliptus Plus Tablet is a combination antidiabetic medication containing Vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and Metformin, a biguanide. This dual-action tablet effectively controls blood glucose levels in adults with type 2 diabetes mellitus. Uses Gliptus Plus Tablet is prescribed for the management of type 2 diabetes mellitus in adult patients whose blood glucose levels are not adequately controlled with metformin alone or who are already being treated with separate tablets of vildagliptin and metformin. Benefits Improved glycemic control through dual mechanisms Reduced risk of hypoglycemia compared to sulfonylureas Weight-neutral or modest weight reduction effects Convenient fixed-dose combination improves adherence Effective HbA1c reduction Lower fasting and postprandial glucose levels Preserves beta-cell function Complementary modes of action enhance efficacy How It Works Gliptus Plus Tablet functions through complementary mechanisms. Vildagliptin inhibits the DPP-4 enzyme, which increases incretin hormone levels, stimulating insulin secretion and reducing glucagon release. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and enhances peripheral glucose uptake and utilization. Duration of Action The therapeutic effects of Vildagliptin last approximately 24 hours, while Metformin’s glucose-lowering effect persists for 8-12 hours. The combination provides sustained glycemic control throughout the day when taken as prescribed. Dosage Condition Recommended Dosage Frequency Initial therapy 50mg/500mg Twice daily Inadequate control on metformin 50mg/1000mg Twice daily Switching from combination therapy Equivalent to current doses Twice daily Warnings Not suitable for patients with type 1 diabetes or diabetic ketoacidosis. Discontinue temporarily before procedures requiring restricted food intake. Risk of lactic acidosis, particularly in patients with kidney dysfunction. Not recommended for patients with severe hepatic impairment or excessive alcohol consumption. Side Effects Common side effects include gastrointestinal disturbances such as nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Other possible effects include mild headache, dizziness, tremor, and metallic taste. Most side effects are mild to moderate and tend to resolve with continued treatment. Pregnancy and Breastfeeding Not recommended during pregnancy or breastfeeding. Alternative insulin therapy is preferred for glycemic control during pregnancy. Women of childbearing potential should use effective contraception during treatment with Gliptus Plus Tablet. Interactions Iodinated contrast agents (increased risk of renal impairment) Alcohol (enhanced hypoglycemic effects and lactic acidosis risk) Corticosteroids (decreased glucose-lowering effect) Diuretics (potential for decreased renal function) ACE inhibitors (may enhance hypoglycemic effect) Cationic drugs (potential competition for renal tubular transport) Beta-blockers (may mask hypoglycemic symptoms) Precautions Regular monitoring of renal function before and during treatment. Vitamin B12 levels should be monitored during long-term use due to potential deficiency. Temporarily discontinue in cases of dehydration, severe infection, or hypoxia. Avoid in patients with history of pancreatitis. Exercise caution in elderly patients. Important Information Take Gliptus Plus Tablet with meals to reduce gastrointestinal side effects. Regular blood glucose monitoring is essential to evaluate treatment efficacy. Hypoglycemia risk is increased when combined with insulin or insulin secretagogues. Maintain adequate hydration during treatment. Product Image Highlights Customer questions & answers Have a question about this product? Your question * Name * Email * Notify me when answered. Recent Popular Unanswered There are no questions yet. Be the first to ask a question about this product. Tailored to Your Needs Galvus Met 50mg/1000mg Tablet x60₦86,000.00Rated 0 out of 5 Galvus Met 50mg/1000mg is used to manage type 2 diabetes... Add to cart Avrophage Tablet 500mg (Metformin) x84₦6,000.00Rated 0 out of 5 Avrophage is used to treat type 2 diabetes mellitus and... Add to cart Glyphage Tablet 500mg (Metformin) x100₦10,000.00Rated 0 out of 5 Glyphage Tablet 500mg is used to manage type 2 diabetes... Add to cart Clamide Tablet 5mg (Glibenclamide) x100₦10,000.00Rated 0 out of 5 Clamide is used for the treatment of type 2 diabetes... Add to cart Cancel replyReview our product to get a chance to receive coupon!Your email address will not be published. Required fields are marked *Your rating Rate… Perfect Good Average Not that bad Very poor Your review * Choose pictures & videos(maxsize: 2000 KB, max files: 5) Choose pictures & videos Your review is being submitted. Please wait a moment Name * Email * Save my name, email, and website in this browser for the next time I comment.
