Glanil Tablet 5mg contains Glibenclamide, a sulfonylurea antidiabetic medication. This oral hypoglycemic agent effectively lowers blood glucose levels in adults with type 2 diabetes mellitus when diet and exercise alone are insufficient. Uses Glanil Tablet treats type 2 diabetes mellitus by controlling elevated blood sugar levels. It’s used when lifestyle modifications including diet and exercise fail to achieve adequate glycemic control. Glanil may be used alone or combined with other antidiabetic medications like metformin for better diabetes management. Benefits Effectively lowers blood glucose levels Reduces HbA1c levels for long-term control Decreases risk of diabetic complications Improves insulin secretion from pancreas Cost-effective diabetes management option Convenient once or twice daily dosing Proven efficacy over decades of use Can be combined with other diabetes medications Helps prevent hyperglycemic episodes How It Works Glanil works by stimulating insulin release from functioning pancreatic beta cells. Glibenclamide binds to sulfonylurea receptors on beta cells, closing ATP-sensitive potassium channels. This causes cell depolarization, calcium influx, and subsequent insulin secretion, effectively lowering blood glucose levels. Dosage Patient Category Initial Dosage Maximum Daily Dosage Adults 2.5-5mg once daily 15mg daily Elderly 2.5mg once daily 10mg daily Take Glanil with breakfast or the first main meal. Dosage should be adjusted gradually based on blood glucose monitoring. Duration of Action Glanil begins working within 1-2 hours of administration, with peak effects occurring at 2-4 hours. The glucose-lowering effect lasts 12-24 hours, allowing once or twice daily dosing. Full therapeutic benefits may take several weeks of consistent use with proper diet and exercise. Side Effects Common side effects include hypoglycemia (low blood sugar), nausea, and weight gain. Some patients experience digestive upset, headache, or dizziness. Rare but serious effects include severe hypoglycemia, allergic reactions, or blood disorders. Symptoms of low blood sugar include sweating, trembling, and confusion. Warning Glanil can cause severe hypoglycemia, especially in elderly patients or with irregular meals. Not suitable for type 1 diabetes or diabetic ketoacidosis. Avoid in patients with severe kidney or liver disease. Risk of hypoglycemia increases with alcohol consumption, strenuous exercise, or missed meals. Pregnancy and Breastfeeding Glanil is contraindicated during pregnancy as it may cause neonatal hypoglycemia. Insulin is the preferred treatment for diabetes during pregnancy. Not recommended during breastfeeding as Glibenclamide passes into breast milk and may affect the infant’s blood sugar levels. Interaction Increased hypoglycemic risk with certain antibiotics and NSAIDs Reduced effectiveness with corticosteroids and thiazide diuretics Enhanced effects when combined with beta-blockers Alcohol may cause severe hypoglycemia or disulfiram-like reaction May interact with warfarin affecting blood clotting Precaution Regular blood glucose monitoring is essential. Carry glucose tablets or candy for hypoglycemia episodes. Use cautiously in elderly patients and those with kidney or liver impairment. Inform healthcare providers before surgery or medical procedures. Maintain consistent meal timing and carbohydrate intake. Important Information Glanil is not a substitute for proper diet and exercise in diabetes management. Always carry diabetic identification. Report signs of infection, unusual fatigue, or persistent nausea to your doctor. Store at room temperature away from moisture and heat. Never share this medication with others even if they have similar symptoms. Product Image Gallery Customer questions & answers Customers say Customers say there is not enough information to provide a summary. AI Generated from customer reviews and questions Have a question about this product? Your question * Name * Email * Notify me when answered. Recent Popular Unanswered There are no questions yet. Be the first to ask a question about this product. Selected with Care, Just for You Actrapid 40IU Injection (Soluble Insulin) x10ml₦18,000.00Rated 0 out of 5 Actrapid 40IU Injection treats Type 1 and Type 2 diabetes... 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